
Hana Dobrovolny, Ph.D.
h.dobrovolny@tcu.edu817-257-6379SWR 142
Program Affiliations
Education
Ph.D (Physics) Duke University, 2008
M.A (Physics) Bryn Mawr College, 2000
B.Sc (Physics and Mathematics) University of Winnipeg, 1997
Areas of Focus
- Computational Biophysics
- Viral infections
- Cancer
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Shetty, A. and Dobrovolny, H.M. (2026). Estimation of SARS-CoV-2 Viral Dynamics Parameters in Favipiravir-Treated Cynomolgus Macaques: Comparison of Individual and Group Average Model Fitting. Pathogens. https://www.mdpi.com/2076-0817/15/10/1007 -
Satani, S. and Dobrovolny, H.M. (2026). Modeling the interferon response to avian influenza. Scientific Reports. https://doi.org/10.1038/s41598-026-71730-9 -
Dobrovolny, H.M. (2026). Mathematical Modeling of Cell-Cell Fusion Assays to Characterize Virus-Mediated Cell Fusion. Advances in Experimental Measurement, (book chapter). https://link.springer.com/chapter/10.1007/978-3-032-22637-2_17 -
Sage, H. and Dobrovolny, H.M. (2026). Exploring the effect of density dependent infection rate in a within host viral infection model. Mathematical Biosciences and Engineering. https://www.aimspress.com/article/doi/10.3934/mbe.2026061 -
Chiarelli, A. and Dobrovolny, H.M. (2026). A mathematical model for temperature effects on virus-mediated cell fusion. Journal of Theoretical Biology. https://www.sciencedirect.com/science/article/abs/pii/S0022519326000366 -
Makam, S. and Dobrovolny, H.M. (2026). Mathematical Modeling of the Role of Cytokines in Sindbis Virus Treatment of Glioblastoma. CPT: Pharmacometrics & Systems Pharmacology. https://ascpt.onlinelibrary.wiley.com/doi/10.1002/psp4.70205 -
Satani, S., Suri, A., and Dobrovolny, H.M. (2025). Mathematical Modeling of Oncolytic Vaccinia Virus Therapy Highlights Neutrophil Impact on Tumor Suppression. Journal of the Royal Society Interface, 22(233):20250481. https://royalsocietypublishing.org/rsif/article/22/233/20250481 -
Mohan, T. and Dobrovolny, H.M. (2025). Mathematical modeling of the effect of multiple vaccines on viral escape. Mathematics and Computers in Simulation. https://www.sciencedirect.com/science/article/abs/pii/S0378475425003829 -
Srivastava, S. and Dobrovolny, H.M. (2025). Quantitative analysis of respiratory viral triple infections: Examining within host dynamics of Influenza, RSV, and SARS-CoV-2. Mathematical Biosciences and Engineering. https://www.aimspress.com/article/doi/10.3934/mbe.2025105 -
Beach, I. and Dobrovolny, H.M. (2025). The effect of antibodies in the presence of syncytia during viral infections. Bulletin of Mathematical Biology, 87:76. https://link.springer.com/article/10.1007/s11538-025-01463-9 -
Gerg, A. and Dobrovolny, H.M. (2025). Quantifying the effect of HIV receptor surface density reveals differences in fusion dynamics of HIV strains. Viruses, 17:583. https://www.mdpi.com/1999-4915/17/4/583 -
Suri, A., Sahani, S., and Dobrovolny, H.M. (2025). Analyzing Dynamical Differences Between Vaccinated and Unvaccinated RSV Patients. Epidemiologia, 6:16. https://www.mdpi.com/2673-3986/6/2/16 -
Botmann, N.K. and Dobrovolny, H.M. (2025). Assessing the Role of Model Choice in Parameter Identifiability of Cancer Treatment Efficacy. Frontiers in Applied Mathematics and Statistics, 11:1542617. https://www.frontiersin.org/journals/applied-mathematics-and-statistics/articles/10.3389/fams.2025.1542617/full -
McCarthy, G. and Dobrovolny, H.M. (2025). Determining the best mathematical model for implementation of NPIs. Mathematical Biosciences and Engineering, 22(3):700-724. https://www.aimspress.com/article/doi/10.3934/mbe.2025026?viewType=HTML -
Dobrovolny, H.M. (2025). How do viruses get around? A review of mathematical modeling of in-host viral transmission. Virology, 604:110444. https://www.sciencedirect.com/science/article/pii/S004268222500056X
Guo, E., S. Satani, A. Suri, R. Padmasolala, S. Makam, T. Yadav, H.M. Dobrovolny, 2025, ``Incorporating the immune response into models of oncolytic virus treatment of cancer'', Society of Mathematical Biology, Edmonton, AB (invited)
Matthews, P., M. Doty, H.M. Dobrovolny, 2025, ``Time-varying viral production in virus dynamics models'', Society of Mathematical Biology, Edmonton, AB (invited)
McCarthy, G., H.M. Dobrovolny, 2025, ``Applications of Mathematical Models of Virus to Mpox'', TSAPS Spring meeting, Houston, TX
Gerg, A., H.M. Dobrovolny, 2025, ``Using alpha shapes to quantify spatial heterogeneity in virus-mediated syncytia formation'', APS Global Summit, Anaheim, CA
Garrett, C., H.M. Dobrovolny, 2025, ``Dynamics of polyaneuploid cancer cell quiescence under stress'', APS Global Summit, Anaheim, CA
Gerg, A., H.M. Dobrovolny, 2025, ``Quantifying Spatial Heterogeneity of Syncytial Cells using Alpha Shapes'', SIAM Conference on Computational Science and Engineering, Fort Worth, TX
Kharki, B., T. McHenry, H.M. Dobrovolny, 2025, ``Identifiability analysis of cancer growth models from dose response curves'', SIAM Conference on Computational Science and Engineering, Fort Worth, TX
McCarthy, G., H.M. Dobrovolny, 2025, ``Identifiability of cell-cell fusion assays'', SIAM Conference on Computational Science and Engineering, Fort Worth, TX
Garrett, C., H.M. Dobrovolny, 2024, ``Dynamics of polyaneuploid cancer cell quiescence under stress'', TSAPS Fall meeting, Dallas, TX
Suri, A., H.M. Dobrovolny, 2024, ``Analyzing Dynamical Differences Between Vaccinated and Unvaccinated'', TSAPS Fall meeting, Dallas, TX
Gerg, A., H.M. Dobrovolny, 2024, ``Quantifying Spatial Heterogeneity of Syncytial Cells'', TSAPS Fall meeting, Dallas, TX (Winner of best graduate poster)
McCarthy, G., H.M. Dobrovolny, 2024, ``Structural and Practical Identifiability Analysis of Models of Scyncytia Formation'', TSAPS Fall meeting, Dallas, TX
Rehmatullah, M., H.M. Dobrovolny, 2024, ``Characterization of a cell-adapted oncolytic virus'', Eastern Great Lakes Section of APS Fall meeting, Marietta, OH
Dobrovolny, H.M., 2024, `` Infectious physics: Using physics to help us understand respiratory viral coinfections'', Texas A&M Commerce physics colloquium,(invited)
McCarthy, G., H.M. Dobrovolny, 2024, ``Structural and Practical Identifiability Analysis of Models for Syncytia Growth'', TSAPS Spring meeting, Stephenville, TX
Gerg, A., H.M. Dobrovolny, 2024, ``Nonlinear Analysis of HIV Type-1 Syncytia Formation'', TSAPS Spring meeting, Stephenville, TX
Amidei, A., H.M. Dobrovolny, 2024, ``Modeling and characterization of virus-mediated cell fusion assays'', TSAPS Spring meeting, Stephenville, TX
Kalra, M., S. Kalra, H.M. Dobrovolny}, 2024, ``Finding the Optimal IFN Response For Oncolytic Virus Treatment'', ABRCMS ePoster Symposium, virtual
Yadav, T., H.M. Dobrovolny, 2024, ``Oncolytic Virus and the Interferon Response'', ABRCMS ePoster Symposium, virtual
Talagadadeeva, S., H.M. Dobrovolny, 2024, ``Modeling of infrared detection of cancer miRNA'', ABRCMS ePoster Symposium, virtual
Amidei, A.}, E. Guo, L. Pinky, B. Fain, H.M. Dobrovolny, 2024, ``Maximizing insight into viral infections using within host mathematical models'', JPS Research & Quality Symposium, Fort Worth, TX
Gerg, A., H.M. Dobrovolny, 2024, ``Density Dependence: A Nonlinear Analysis of HIV Syncytium in Drug-Treated Transfection'', JPS Research & Quality Symposium, Fort Worth, TX
Dobrovolny, H.M., 2024, ``Syncytia formation: The dynamics of virus-mediated cell fusion'', Idaho State University physics colloquium, virtual (invited)
Amidei, A., G. McCarthy, H.M. Dobrovolny, 2024, ``Modeling and characterization of virus-mediated cell fusion assays'', APS March meeting, Minneapolis, MN
Sage, H., H.M. Dobrovolny, 2024, ``The effect of density-dependent infection on ODE models of viral dynamics'', APS March meeting, Minneapolis, MN
- Society for Mathematical Biology
- American Physical Society
- Canadian Association of Physicists
- American Association of Physics Teachers
- Society for Industrial and Applied Mathematics
- Advanced Laboratory Physics Association
- Sigma Xi
Last Updated: October 02, 2026